Common Questions and Answers about Prevacid and pepcid together prevacid If positive, then the anti-acid medication can be optimized - perhaps a combination of Prevacid and an H2 blocker (like Zantac or Pepcid ). Prevacid vs Prilosec comparison. Both Prevacid and Prilosec are proton pump inhibitors that work by inhibiting the proton pumps in the stomach that produce acid. They treat the same medical issues, those primarily associated with over-production of acid in the stomach and the resultant ef. Compare Pepcid AC vs. Prevacid, which is better for uses like: Reflux, GERD and Heartburn. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Pepcid AC 4.5/5 over Prevacid 4/5 in overall satisfaction. Proton pumps are enzymes found in the parietal cells of your stomach. They make hydrochloric acid, the main ingredient of stomach acid. Your body needs stomach acid for digestion. I started quite a few years ago on aciphex, that helped quite a bit but after a while seemed to lose its effectiveness. Dr switched me to Prilosec and that also seemed to work for quite a while. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids. Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers. PEPCID Complete® combines an H2 Blocker with an antacid that starts neutralizing acid in seconds, so it works even faster. Because the faster it starts relieving heartburn, the better. Because the faster it starts relieving heartburn, the better. Compare Pepcid vs. Prevacid, which is better for uses like: Reflux, GERD and Heartburn. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Pepcid and Prevacid evenly with 4/5. Pepcid is in a group called H2 inhibitors and prilosec is in the group called proton pump inhibitors. They both block the production and use of stomach acid, in slightly different ways. For some pepcid doesn't work as well as prilosec, but for many it does. The H2 inhibitors are the older of the meds. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Chiu on prilosec vs pepcid.To what will help with a distended abdomen depends entirely on the cause of the distention. Probiotics are helpful with a lot of digestive issues, if you take them regularly. The two meds you mention reduce stomach acid and are unlikely to help with distention. If this is happening.